- Automation, AI, and cloud computing fuel new small and midsize business (SMB) opportunities.
- Niche solutions in FinTech, EdTech, and biotech enable small businesses to expand.
- EV and semiconductor industries offer supply chain growth potential.
Emerging technology, shifting regulations, and evolving customer expectations are changing the small business landscape. Which industry will thrive in 2026? Here are some sectors to watch and how small businesses can capture growth opportunities:
Automation and Robotics
Automation is increasingly impacting every aspect of our lives. Small businesses may be able to capture opportunities by providing niche solutions, such as robotics for small-scale manufacturing, warehouse operations, or healthcare applications. For example, the global healthcare automation market is projected to grow from $38.6 billion in 2023 to $94 billion by the end of 2033 at a 9.3% compound annual growth rate (CAGR).[1] Moreover, service businesses may be able to grow their revenue streams by offering installation, maintenance, and customization for robotics systems.
Artificial Intelligence (AI) and Cloud Computing
Cloud computing has accelerated AI adoption, making new capabilities accessible to individuals and companies of all sizes. The global AI market size was $87.27 billion in 2024 and is projected to reach $647.6 billion by 2030, at a CAGR of 39.7%.[2] Besides adopting AI themselves, small businesses in the IT field may be able to help clients build and implement specialized platforms and applications, like AI-driven analytics for specific industries, cloud-based collaboration suites, or compliance-focused SaaS products.
If you plan to venture into this area, consider the complexity and the time to generate revenue. For example, you may have to jump through more hoops (e.g., legal and compliance) when implementing AI capabilities for large companies. On the other hand, you will likely see a faster return path by working with SMB clients.
Financial Technology (FinTech)
From payments and insurtech to cybersecurity and regtech, the global fintech market saw $44.7 billion in investment during H1 2025, with a growing focus on AI-enabled applications.[3] The industry is ripe for SMB innovators, for example, to help companies embed finance tools in existing e-commerce or gig economy platforms. Additionally, demand for niche compliance solutions, fraud prevention, and cross-border payment services is expected to increase, offering opportunities for smaller firms to enter the market.
Education Technology (EdTech)
The rise in remote learning offers opportunities to launch scalable businesses with relatively low entry barriers. For example, you may develop industry-specific solutions, tools for vocational training, or AI-powered tutoring. Meanwhile, demand for digital curriculum content, corporate upskilling programs, gamified learning, and hybrid learning infrastructure for schools and universities is expected to increase, presenting opportunities for innovators to combine emerging technologies to enhance learning experiences.
Biotechnology for Personalized Medicine
Advances in genomics, diagnostics, AI for therapy matching, and personalized nutrition accelerate personalization in healthcare, with the global personalized medicine market projected to grow from $88.21 billion in 2025 to $206.23 billion by 2033, exhibiting a CAGR of 11.2%.[4] Small businesses may be able to enter this field by focusing on specialized services, such as genetic testing or diagnostic tools for specific conditions. You may also offer personalized nutrition and wellness programs tied to genomic insights or partner with research institutions and hospitals to broaden your reach.
Hybrid and Electric Vehicle (EV) Manufacturing
24% of vehicle shoppers say they're "very likely" to consider purchasing an EV.[5] Although large automakers dominate mass manufacturing, SMBs may be able to carve out value in the supply chain. You may find opportunities in battery component manufacturing, EV charging infrastructure, supply chain parts, and retrofitting services. Moreover, demand for service support (e.g., EV maintenance and software) is poised to increase, opening opportunities for small businesses to expand their offerings and capture more revenue.
Semiconductor Manufacturing
Semiconductors are the backbone of many technologies, including AI, EV, cloud computing, Internet of Things (IoT), and communication infrastructure. While building large fabrication plants is very capital-intensive, small businesses may be able to find opportunities in providing semiconductor materials or design and testing services. Additionally, you may be able to serve niche markets by offering custom solutions for sensors, power management chips, and IoT devices.
Prepare for a Successful Year Ahead
To capture new opportunities, small businesses may want to invest in training and grow their ecosystems to create partnerships and synergy. Identify niches to focus your resources and stay current with policy and incentives in fast-growing industries. Additionally, work with a trusted banking partner like PNC, which understands the SMB landscape, to help you explore financing options and maintain your financial health for sustainable growth. Schedule an appointment with an experienced banker to see how we can help you set the stage for success.
